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Neuraxial timing on antithrombotic therapy
Published hold intervals for a neuraxial or deep plexus block, a catheter removal, or the first dose after one, in an ADULT patient. The guideline states obstetric practice separately and this table does not carry it. The interval is the guideline's; the decision to proceed is not, and stays with the clinician.
Your local time.
Enter the time of last dose to see the earliest permissible time.
- A residual apixaban plasma level below 30 ng/mL, or a residual anti-Xa activity level at or below 0.1 IU/mL, is the alternative the guideline states to waiting the full interval.
- After a traumatic (bloody) puncture the manufacturer states a 48 hour delay before the next apixaban dose.
Intervals are the published minima for the stated agent, dose tier, and event. They do not decide whether a block may proceed: concurrent drugs that affect hemostasis, the puncture itself, and the patient's own risk all sit outside this arithmetic.